{"id":807,"date":"2019-04-10T22:52:47","date_gmt":"2019-04-11T03:52:47","guid":{"rendered":"https:\/\/www.ozonoterapia-peru.org\/?page_id=807"},"modified":"2019-11-15T01:41:29","modified_gmt":"2019-11-15T06:41:29","slug":"estudios-cientificos","status":"publish","type":"page","link":"https:\/\/www.ozonoterapia-peru.org\/?page_id=807","title":{"rendered":"Estudios cient\u00edficos"},"content":{"rendered":"<div class=\"pmid-refs\"><ul><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41893196\/\" target=\"_blank\" rel=\"noopener noreferrer\">Single-Step Extrusion Printing of Microgrooved Annulus Fibrosus Scaffolds via Patterned Nozzles.<\/a><br><small><strong>Authors:<\/strong> Kluser N, Alig GU, Sprecher C, Woods X, Grad S, Alini M, H\u00e4ckel S, Albers CE, Eglin D, Narayanan R, Vernengo AJ<\/small><br><small><strong>Published:<\/strong> 2026 Mar 11<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41772594\/\" target=\"_blank\" rel=\"noopener noreferrer\">TIE2-positive cells in the nucleus pulposus with a purpose: the who, what and why.<\/a><br><small><strong>Authors:<\/strong> Schol J, Ambrosio L, Ruiz-Fernandez C, Schlagenhof L, Voskamp C, Laagland LT, Matsushita E, Soma H, Warita T, Vadal\u00e0 G, Tryfonidou MA, Gantenbein B, Sakai D<\/small><br><small><strong>Published:<\/strong> 2026 Mar 2<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41101337\/\" target=\"_blank\" rel=\"noopener noreferrer\">Aligned nanofibrous patch for sustained nicardipine delivery and enhanced chondrogenic differentiation in annulus fibrosus repair.<\/a><br><small><strong>Authors:<\/strong> Deekshika S, Sumi VS, Vellara JF, Cr R, Nair M<\/small><br><small><strong>Published:<\/strong> 2025 Oct 29<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40773150\/\" target=\"_blank\" rel=\"noopener noreferrer\">Exosome Therapy: A Promising Avenue for Treating Intervertebral Disc Degeneration.<\/a><br><small><strong>Authors:<\/strong> Bhat S, Kannan S, Kolkundkar UK, Seetharam RN<\/small><br><small><strong>Published:<\/strong> 2025 Oct<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40717265\/\" target=\"_blank\" rel=\"noopener noreferrer\">14. Discogenic Low Back Pain.<\/a><br><small><strong>Authors:<\/strong> van Os WKM, Alvarez-Jimenez R, Cohen SP, Stojanovic MP, Ruiz-Lopez R, Van Zundert J, Kallewaard JW<\/small><br><small><strong>Published:<\/strong> 2025 Sep<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40474857\/\" target=\"_blank\" rel=\"noopener noreferrer\">Advances in Annulus Fibrosus Repair: Hybrid Scaffolds and Fabrication Techniques for Regeneration.<\/a><br><small><strong>Authors:<\/strong> ADaLi ML, Nie MD, Zhang Q, Li YD, Yang QQ, Fang F, Cheng CK<\/small><br><small><strong>Published:<\/strong> 2025 Jun 5<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40389238\/\" target=\"_blank\" rel=\"noopener noreferrer\">Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models.<\/a><br><small><strong>Authors:<\/strong> Yang S, Soheilmoghaddam F, Pivonka P, Li J, Rudd S, Yeo T, Tu J, Zhu Y, Cooper-White JJ<\/small><br><small><strong>Published:<\/strong> 2025 Sep<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40308883\/\" target=\"_blank\" rel=\"noopener noreferrer\">Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors.<\/a><br><small><strong>Authors:<\/strong> Li ZP, Li H, Ruan YH, Wang P, Zhu MT, Fu WP, Wang RB, Tang XD, Zhang Q, Li SL, Yin H, Li CJ, Tian YG, Han RN, Wang YB, Zhang CJ<\/small><br><small><strong>Published:<\/strong> 2025 Apr 26<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40237326\/\" target=\"_blank\" rel=\"noopener noreferrer\">A self-powered sandwich-structured scaffold with dual-electroactive properties to regenerate damaged intervertebral discs after discectomy.<\/a><br><small><strong>Authors:<\/strong> Wang J, Huang L, Guo T, Liu Z, Xu H, Yang H, Liu L, Feng G, Zhang L<\/small><br><small><strong>Published:<\/strong> 2025 May 7<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40169595\/\" target=\"_blank\" rel=\"noopener noreferrer\">Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.<\/a><br><small><strong>Authors:<\/strong> Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M<\/small><br><small><strong>Published:<\/strong> 2025 Apr 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40119681\/\" target=\"_blank\" rel=\"noopener noreferrer\">Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.<\/a><br><small><strong>Authors:<\/strong> Wang M, He Z, Wang A, Sun S, Li J, Liu F, Li C, Yang C, Lei J, Yu Y, Ma S, Wang S, Zhang W, Yu Z, Liu GH, Qu J<\/small><br><small><strong>Published:<\/strong> 2025 Aug 7<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39940049\/\" target=\"_blank\" rel=\"noopener noreferrer\">Pyroptosis: candidate key targets for mesenchymal stem cell-derived exosomes for the treatment of bone-related diseases.<\/a><br><small><strong>Authors:<\/strong> Li H, Zhang P, Lin M, Li K, Zhang C, He X, Gao K<\/small><br><small><strong>Published:<\/strong> 2025 Feb 12<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38891119\/\" target=\"_blank\" rel=\"noopener noreferrer\">Bone Marrow Aspirate Concentrate Combined with Ultra-Purified Alginate Bioresorbable Gel Enhances Intervertebral Disc Repair in a Canine Model: A Preclinical Proof-of-Concept Study.<\/a><br><small><strong>Authors:<\/strong> Ukeba D, Ishikawa Y, Yamada K, Ohnishi T, Tachi H, Tha KK, Iwasaki N, Sudo H<\/small><br><small><strong>Published:<\/strong> 2024 Jun 5<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38707134\/\" target=\"_blank\" rel=\"noopener noreferrer\">Exosomes for the Management of Low Back Pain: A Review of Current Clinical Evidence.<\/a><br><small><strong>Authors:<\/strong> Gupta A<\/small><br><small><strong>Published:<\/strong> 2024 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38555831\/\" target=\"_blank\" rel=\"noopener noreferrer\">Remarkable recovery of lower extremity motor impairment in degenerative disc disease after percutaneous laser disc decompression combined with umbilical cord-derived mesenchymal stem cells implantation: A case report.<\/a><br><small><strong>Authors:<\/strong> Rahyussalim AJ, Andar AA, Canintika AF, Putri DA, Kurniawati T<\/small><br><small><strong>Published:<\/strong> 2024 May<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38475906\/\" target=\"_blank\" rel=\"noopener noreferrer\">Menstrual blood-derived mesenchymal stem cells combined with collagen I gel as a regenerative therapeutic strategy for degenerated disc after discectomy in rats.<\/a><br><small><strong>Authors:<\/strong> Yu L, Wu H, Zeng S, Hu X, Wu Y, Zhou J, Yuan L, Zhang Q, Xiang C, Feng Z<\/small><br><small><strong>Published:<\/strong> 2024 Mar 13<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38283179\/\" target=\"_blank\" rel=\"noopener noreferrer\">Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus-like cell phenotype.<\/a><br><small><strong>Authors:<\/strong> Peredo AP, Tsinman TK, Bonnevie ED, Jiang X, Smith HE, Gullbrand SE, Dyment NA, Mauck RL<\/small><br><small><strong>Published:<\/strong> 2024 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38227139\/\" target=\"_blank\" rel=\"noopener noreferrer\">Future of low back pain: unravelling IVD components and MSCs&#039; potential.<\/a><br><small><strong>Authors:<\/strong> Le\u00e3o Monteiro R<\/small><br><small><strong>Published:<\/strong> 2024 Jan 16<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38171273\/\" target=\"_blank\" rel=\"noopener noreferrer\">Percutaneous laser disc decompression combined with secretome of umbilical cord-derived mesenchymal stem cells in a patient with spinal cord injury: A case report.<\/a><br><small><strong>Authors:<\/strong> Rahyussalim AJ, Priyono AH, Budhy F, Muntaha M, Ramadhani R, Canintika AF<\/small><br><small><strong>Published:<\/strong> 2024 Jan<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37918699\/\" target=\"_blank\" rel=\"noopener noreferrer\">Biological Therapeutic Modalities for Intervertebral Disc Diseases: An Orthoregeneration Network (ON) Foundation Review.<\/a><br><small><strong>Authors:<\/strong> Mizuno S, Vadala G, Kang JD<\/small><br><small><strong>Published:<\/strong> 2024 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37810753\/\" target=\"_blank\" rel=\"noopener noreferrer\">Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration.<\/a><br><small><strong>Authors:<\/strong> Hu X, Tian X, Yang C, Ling F, Liu H, Zhu X, Pei M, Yang H, Liu T, Xu Y, He F<\/small><br><small><strong>Published:<\/strong> 2023 Dec<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37760908\/\" target=\"_blank\" rel=\"noopener noreferrer\">Signaling Mechanisms of Stem Cell Therapy for Intervertebral Disc Degeneration.<\/a><br><small><strong>Authors:<\/strong> Du X, Liang K, Ding S, Shi H<\/small><br><small><strong>Published:<\/strong> 2023 Sep 6<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37200907\/\" target=\"_blank\" rel=\"noopener noreferrer\">Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-\u03baB inflammatory pathway.<\/a><br><small><strong>Authors:<\/strong> Wang P, Yang C, Lu J, Ren Y, Goltzman D, Miao D<\/small><br><small><strong>Published:<\/strong> 2023 May<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37150986\/\" target=\"_blank\" rel=\"noopener noreferrer\">Exosome-mediated Repair of Intervertebral Disc Degeneration: The Potential Role of miRNAs.<\/a><br><small><strong>Authors:<\/strong> Wang HS, Lin S, Yu HM<\/small><br><small><strong>Published:<\/strong> 2024<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37047511\/\" target=\"_blank\" rel=\"noopener noreferrer\">The Use of Medical Ozone in Chronic Intervertebral Disc Degeneration Can Be an Etiological and Conservative Treatment.<\/a><br><small><strong>Authors:<\/strong> Grangeat AM, Erario MLA<\/small><br><small><strong>Published:<\/strong> 2023 Mar 31<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36988365\/\" target=\"_blank\" rel=\"noopener noreferrer\">Pain Relief After Allogenic Stem Cell Disc Therapy.<\/a><br><small><strong>Authors:<\/strong> Lewandrowski KU, Dowling A, Vera JC, Leon JFR, Telfeian AE, Lorio MP<\/small><br><small><strong>Published:<\/strong> 2023 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36731929\/\" target=\"_blank\" rel=\"noopener noreferrer\">Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre, prospective, double-blind randomised controlled trial.<\/a><br><small><strong>Authors:<\/strong> Sudo H, Miyakoshi T, Watanabe Y, Ito YM, Kahata K, Tha KK, Yokota N, Kato H, Terada T, Iwasaki N, Arato T, Sato N, Isoe T<\/small><br><small><strong>Published:<\/strong> 2023 Feb 2<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36655116\/\" target=\"_blank\" rel=\"noopener noreferrer\">Comprehensive narrative review on the analysis of outcomes from cell transplantation clinical trials for discogenic low back pain.<\/a><br><small><strong>Authors:<\/strong> Schol J, Sakai D<\/small><br><small><strong>Published:<\/strong> 2023 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36506585\/\" target=\"_blank\" rel=\"noopener noreferrer\">Gene expression profiling in nucleus pulposus of human ruptured lumbar disc herniation.<\/a><br><small><strong>Authors:<\/strong> Li X, Shen X, Wang Z, Jiang H, Ma Z, Yu P, Yu Z, Qian X, Liu J<\/small><br><small><strong>Published:<\/strong> 2022<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35537547\/\" target=\"_blank\" rel=\"noopener noreferrer\">Decellularized extracellular matrix-based scaffold and hypoxic priming: A promising combination to improve the phenotype of degenerate intervertebral disc cells.<\/a><br><small><strong>Authors:<\/strong> Penolazzi L, Lambertini E, D&#039;Agostino S, Pozzobon M, Notarangelo MP, Greco P, De Bonis P, Nastruzzi C, Piva R<\/small><br><small><strong>Published:<\/strong> 2022 Jul 15<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35486489\/\" target=\"_blank\" rel=\"noopener noreferrer\">Treatment of Intervertebral Disc Degeneration.<\/a><br><small><strong>Authors:<\/strong> Xin J, Wang Y, Zheng Z, Wang S, Na S, Zhang S<\/small><br><small><strong>Published:<\/strong> 2022 Jul<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35427416\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intradiscal Injection of Autologous Discogenic Cells in Patients with Discectomy: A Prospective Clinical Study of Its Safety and Feasibility.<\/a><br><small><strong>Authors:<\/strong> Xuan A, Ruan D, Wang C, He Q, Wang D, Hou L, Zhang C, Li C, Ji W, Wen T, Xu C, Zhu Z<\/small><br><small><strong>Published:<\/strong> 2022 May 27<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35409417\/\" target=\"_blank\" rel=\"noopener noreferrer\">Direct Reprogramming and Induction of Human Dermal Fibroblasts to Differentiate into iPS-Derived Nucleus Pulposus-like Cells in 3D Culture.<\/a><br><small><strong>Authors:<\/strong> Seki S, Iwasaki M, Makino H, Yahara Y, Miyazaki Y, Kamei K, Futakawa H, Nogami M, Tran Canh Tung N, Hirokawa T, Tsuji M, Kawaguchi Y<\/small><br><small><strong>Published:<\/strong> 2022 Apr 6<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35208590\/\" target=\"_blank\" rel=\"noopener noreferrer\">Clinical Development of Regenerative Medicine Targeted for Intervertebral Disc Disease.<\/a><br><small><strong>Authors:<\/strong> Sakai D, Schol J, Watanabe M<\/small><br><small><strong>Published:<\/strong> 2022 Feb 10<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35178382\/\" target=\"_blank\" rel=\"noopener noreferrer\">Sa12b Improves Biological Activity of Human Degenerative Nucleus Pulposus Mesenchymal Stem Cells in a Severe Acid Environment by Inhibiting Acid-Sensitive Ion Channels.<\/a><br><small><strong>Authors:<\/strong> Wang Z, Han L, Chen H, Zhang S, Zhang S, Zhang H, Li Y, Tao H, Li J<\/small><br><small><strong>Published:<\/strong> 2022<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35155408\/\" target=\"_blank\" rel=\"noopener noreferrer\">Interleukin-1\u03b2 More Than Mechanical Loading Induces a Degenerative Phenotype in Human Annulus Fibrosus Cells, Partially Impaired by Anti-Proteolytic Activity of Mesenchymal Stem Cell Secretome.<\/a><br><small><strong>Authors:<\/strong> Gon\u00e7alves RM, Saggese T, Yong Z, Ferreira JR, Ignatius A, Wilke HJ, Neidlinger-Wilke C, Teixeira GQ<\/small><br><small><strong>Published:<\/strong> 2021<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35101851\/\" target=\"_blank\" rel=\"noopener noreferrer\">Mesenchymal stromal\/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier.<\/a><br><small><strong>Authors:<\/strong> Widjaja G, Jalil AT, Budi HS, Abdelbasset WK, Efendi S, Suksatan W, Rita RS, Satria AP, Aravindhan S, Saleh MM, Shalaby MN, Yumashev AV<\/small><br><small><strong>Published:<\/strong> 2022 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35085848\/\" target=\"_blank\" rel=\"noopener noreferrer\">Combination of ultra-purified stem cells with an in situ-forming bioresorbable gel enhances intervertebral disc regeneration.<\/a><br><small><strong>Authors:<\/strong> Ukeba D, Yamada K, Suyama T, Lebl DR, Tsujimoto T, Nonoyama T, Sugino H, Iwasaki N, Watanabe M, Matsuzaki Y, Sudo H<\/small><br><small><strong>Published:<\/strong> 2022 Feb<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34376495\/\" target=\"_blank\" rel=\"noopener noreferrer\">Stem Cells and Intervertebral Disc Regeneration Overview-What They Can and Can&#039;t Do.<\/a><br><small><strong>Authors:<\/strong> Vadal\u00e0 G, Ambrosio L, Russo F, Papalia R, Denaro V<\/small><br><small><strong>Published:<\/strong> 2021 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34352363\/\" target=\"_blank\" rel=\"noopener noreferrer\">The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review.<\/a><br><small><strong>Authors:<\/strong> Schneider BJ, Hunt C, Conger A, Qu W, Maus TP, Vorobeychik Y, Cheng J, Duszynski B, McCormick ZL<\/small><br><small><strong>Published:<\/strong> 2022 Feb<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34337012\/\" target=\"_blank\" rel=\"noopener noreferrer\">Selective Retention of Bone Marrow Stromal Cells with Gelatin Sponge for Repair of Intervertebral Disc Defects after Microendoscopic Discectomy: A Prospective Controlled Study and 2-Year Follow-Up.<\/a><br><small><strong>Authors:<\/strong> Xu B, Zhang H, Du L, Yuan Q, Zhang K, Xu H, Ma X, Liu Y, Jiang H, Li N<\/small><br><small><strong>Published:<\/strong> 2021<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34306116\/\" target=\"_blank\" rel=\"noopener noreferrer\">Percutaneous transplantation of allogenic bone marrow-derived mesenchymal stem cells for the management of paraplegia secondary to Hansen type I intervertebral disc herniation in a Beagle dog.<\/a><br><small><strong>Authors:<\/strong> Sharun K, Kumar R, Chandra V, Saxena AC, Pawde AM, Kinjavdekar P, Dhama K, Amarpal, Sharma GT<\/small><br><small><strong>Published:<\/strong> 2021 Spring<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33989456\/\" target=\"_blank\" rel=\"noopener noreferrer\">Long-term pre-clinical evaluation of an injectable chitosan nanocellulose hydrogel with encapsulated adipose-derived stem cells in an ovine model for IVD regeneration.<\/a><br><small><strong>Authors:<\/strong> Schmitt C, Radetzki F, Stirnweiss A, Mendel T, Ludtka C, Friedmann A, Baerthel A, Brehm W, Milosevic J, Meisel HJ, Goehre F, Schwan S<\/small><br><small><strong>Published:<\/strong> 2021 Jul<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33946902\/\" target=\"_blank\" rel=\"noopener noreferrer\">Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells.<\/a><br><small><strong>Authors:<\/strong> Sako K, Sakai D, Nakamura Y, Schol J, Matsushita E, Warita T, Horikita N, Sato M, Watanabe M<\/small><br><small><strong>Published:<\/strong> 2021 Apr 29<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33488928\/\" target=\"_blank\" rel=\"noopener noreferrer\">Exosomes Derived from Human Urine-Derived Stem Cells Inhibit Intervertebral Disc Degeneration by Ameliorating Endoplasmic Reticulum Stress.<\/a><br><small><strong>Authors:<\/strong> Xiang H, Su W, Wu X, Chen W, Cong W, Yang S, Liu C, Qiu C, Yang SY, Wang Y, Zhang G, Guo Z, Xing D, Chen B<\/small><br><small><strong>Published:<\/strong> 2020<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33481466\/\" target=\"_blank\" rel=\"noopener noreferrer\">Bone Marrow Aspirate Concentrate Combined with in Situ Forming Bioresorbable Gel Enhances Intervertebral Disc Regeneration in Rabbits.<\/a><br><small><strong>Authors:<\/strong> Ukeba D, Yamada K, Tsujimoto T, Ura K, Nonoyama T, Iwasaki N, Sudo H<\/small><br><small><strong>Published:<\/strong> 2021 Apr 21<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33459443\/\" target=\"_blank\" rel=\"noopener noreferrer\">Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt\/autophagy.<\/a><br><small><strong>Authors:<\/strong> Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y<\/small><br><small><strong>Published:<\/strong> 2021 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33163421\/\" target=\"_blank\" rel=\"noopener noreferrer\">Evaluation of Bone Marrow-derived Stem Cells and Adipose-derived Stem Cells Co-cultured on Human Nucleus Pulposus Cells: A Pilot Study.<\/a><br><small><strong>Authors:<\/strong> Yoon SH, Kim DH, Cho S, Kim KJ<\/small><br><small><strong>Published:<\/strong> 2020 Oct<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32975235\/\" target=\"_blank\" rel=\"noopener noreferrer\">Expansion and characterization of cells from surgically removed intervertebral disc fragments in xenogen-free medium.<\/a><br><small><strong>Authors:<\/strong> Mujawar S, Iyengar K, Nadkarni S, Mulherkar R<\/small><br><small><strong>Published:<\/strong> 2020<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32613166\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations.<\/a><br><small><strong>Authors:<\/strong> Agha O, Mueller-Immergluck A, Liu M, Zhang H, Theologis AA, Clark A, Kim HT, Liu X, Feeley BT, Bailey JF<\/small><br><small><strong>Published:<\/strong> 2020 Jun<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32244936\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intervertebral Disc Diseases PART 2: A Review of the Current Diagnostic and Treatment Strategies for Intervertebral Disc Disease.<\/a><br><small><strong>Authors:<\/strong> Wu PH, Kim HS, Jang IT<\/small><br><small><strong>Published:<\/strong> 2020 Mar 20<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32211592\/\" target=\"_blank\" rel=\"noopener noreferrer\">The transcription factors regulating intervertebral disc development.<\/a><br><small><strong>Authors:<\/strong> Nakamichi R, Asahara H<\/small><br><small><strong>Published:<\/strong> 2020 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32143180\/\" target=\"_blank\" rel=\"noopener noreferrer\">Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs.<\/a><br><small><strong>Authors:<\/strong> Ukeba D, Sudo H, Tsujimoto T, Ura K, Yamada K, Iwasaki N<\/small><br><small><strong>Published:<\/strong> 2020 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32125276\/\" target=\"_blank\" rel=\"noopener noreferrer\">p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle.<\/a><br><small><strong>Authors:<\/strong> Che H, Li J, Li Y, Ma C, Liu H, Qin J, Dong J, Zhang Z, Xian CJ, Miao D, Wang L, Ren Y<\/small><br><small><strong>Published:<\/strong> 2020 Mar 3<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31981764\/\" target=\"_blank\" rel=\"noopener noreferrer\">Reduced nucleotomy-induced intervertebral disc disruption through spontaneous spheroid formation by the Low Adhesive Scaffold Collagen (LASCol).<\/a><br><small><strong>Authors:<\/strong> Takeoka Y, Yurube T, Morimoto K, Kunii S, Kanda Y, Tsujimoto R, Kawakami Y, Fukase N, Takemori T, Omae K, Kakiuchi Y, Miyazaki S, Kakutani K, Takada T, Nishida K, Fukushima M, Kuroda R<\/small><br><small><strong>Published:<\/strong> 2020 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31885875\/\" target=\"_blank\" rel=\"noopener noreferrer\">Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells.<\/a><br><small><strong>Authors:<\/strong> Torre OM, Mroz V, Benitez ARM, Huang AH, Iatridis JC<\/small><br><small><strong>Published:<\/strong> 2019<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31781580\/\" target=\"_blank\" rel=\"noopener noreferrer\">Comparison of the Efficacy of Surgical Decompression Alone and Combined With Canine Adipose Tissue-Derived Stem Cell Transplantation in Dogs With Acute Thoracolumbar Disk Disease and Spinal Cord Injury.<\/a><br><small><strong>Authors:<\/strong> Bach FS, Rebelatto CLK, Fracaro L, Senegaglia AC, Fragoso FYI, Daga DR, Brofman PRS, Pimp\u00e3o CT, Engracia Filho JR, Montiani-Ferreira F, Villanova JA Jr<\/small><br><small><strong>Published:<\/strong> 2019<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31730570\/\" target=\"_blank\" rel=\"noopener noreferrer\">Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response.<\/a><br><small><strong>Authors:<\/strong> Wangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M, Grad S<\/small><br><small><strong>Published:<\/strong> 2019 Dec 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30703615\/\" target=\"_blank\" rel=\"noopener noreferrer\">Combination of stem cells from deciduous teeth and electroacupuncture for therapy in dogs with chronic spinal cord injury: A pilot study.<\/a><br><small><strong>Authors:<\/strong> Prado C, Fratini P, de S\u00e1 Schiavo Matias G, Bocabello RZ, Monteiro J, Dos Santos CJ Jr, Joaquim JGF, Giglio RF, Possebon FS, Sakata SH, Miglino MA<\/small><br><small><strong>Published:<\/strong> 2019 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30597057\/\" target=\"_blank\" rel=\"noopener noreferrer\">Office-Based Mesenchymal Stem Cell Therapy for the Treatment of Musculoskeletal Disease: A Systematic Review of Recent Human Studies.<\/a><br><small><strong>Authors:<\/strong> Law L, Hunt CL, van Wijnen AJ, Nassr A, Larson AN, Eldrige JS, Mauck WD, Pingree MJ, Yang J, Muir CW, Erwin PJ, Bydon M, Qu W<\/small><br><small><strong>Published:<\/strong> 2019 Aug 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30488736\/\" target=\"_blank\" rel=\"noopener noreferrer\">Treatment of Naturally Degenerated Canine Lumbosacral Intervertebral Discs with Autologous Mesenchymal Stromal Cells and Collagen Microcarriers: A Prospective Clinical Study.<\/a><br><small><strong>Authors:<\/strong> Steffen F, Bertolo A, Affentranger R, Ferguson SJ, Stoyanov J<\/small><br><small><strong>Published:<\/strong> 2019 Feb<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30415465\/\" target=\"_blank\" rel=\"noopener noreferrer\">Autogenic mesenchymal stem cells for intervertebral disc regeneration.<\/a><br><small><strong>Authors:<\/strong> Migliorini F, Rath B, Tingart M, Baroncini A, Quack V, Eschweiler J<\/small><br><small><strong>Published:<\/strong> 2019 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30035326\/\" target=\"_blank\" rel=\"noopener noreferrer\">Impact of Wnt signals on human intervertebral disc cell regeneration.<\/a><br><small><strong>Authors:<\/strong> Pizzute T, He F, Zhang XB, Pei M<\/small><br><small><strong>Published:<\/strong> 2018 Dec<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29959012\/\" target=\"_blank\" rel=\"noopener noreferrer\">In vitro efficacy of silk sericin microparticles and platelet lysate for intervertebral disk regeneration.<\/a><br><small><strong>Authors:<\/strong> Bari E, Perteghella S, Marrubini G, Sorrenti M, Catenacci L, Tripodo G, Mastrogiacomo M, Mandracchia D, Trapani A, Farag\u00f2 S, Gaetani P, Torre ML<\/small><br><small><strong>Published:<\/strong> 2018 Oct 15<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29937524\/\" target=\"_blank\" rel=\"noopener noreferrer\">Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model.<\/a><br><small><strong>Authors:<\/strong> Frauchiger DA, May RD, Bakirci E, Tekari A, Chan SCW, W\u00f6ltje M, Benneker LM, Gantenbein B<\/small><br><small><strong>Published:<\/strong> 2018 Jun 24<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29858667\/\" target=\"_blank\" rel=\"noopener noreferrer\">Bone mesenchymal stem cells attenuate radicular pain by inhibiting microglial activation in a rat noncompressive disk herniation model.<\/a><br><small><strong>Authors:<\/strong> Huang X, Wang W, Liu X, Xi Y, Yu J, Yang X, Ye X<\/small><br><small><strong>Published:<\/strong> 2018 Oct<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29199605\/\" target=\"_blank\" rel=\"noopener noreferrer\">Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.<\/a><br><small><strong>Authors:<\/strong> Serakinci N, Savtekin G<\/small><br><small><strong>Published:<\/strong> 2017<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29055739\/\" target=\"_blank\" rel=\"noopener noreferrer\">Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy.<\/a><br><small><strong>Authors:<\/strong> Daly CD, Ghosh P, Zannettino ACW, Badal T, Shimmon R, Jenkin G, Oehme D, Jain K, Sher I, Vais A, Cohen C, Chandra RV, Goldschlager T<\/small><br><small><strong>Published:<\/strong> 2018 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28993681\/\" target=\"_blank\" rel=\"noopener noreferrer\">Equiaxial Strain Modulates Adipose-derived Stem Cell Differentiation within 3D Biphasic Scaffolds towards Annulus Fibrosus.<\/a><br><small><strong>Authors:<\/strong> Elsaadany M, Winters K, Adams S, Stasuk A, Ayan H, Yildirim-Ayan E<\/small><br><small><strong>Published:<\/strong> 2017 Oct 9<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28939169\/\" target=\"_blank\" rel=\"noopener noreferrer\">Immunomodulation of mesenchymal stem cells in discogenic pain.<\/a><br><small><strong>Authors:<\/strong> Migu\u00e9lez-Rivera L, P\u00e9rez-Castrillo S, Gonz\u00e1lez-Fern\u00e1ndez ML, Prieto-Fern\u00e1ndez JG, L\u00f3pez-Gonz\u00e1lez ME, Garc\u00eda-Cosamal\u00f3n J, Villar-Su\u00e1rez V<\/small><br><small><strong>Published:<\/strong> 2018 Feb<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28678109\/\" target=\"_blank\" rel=\"noopener noreferrer\">Age-Correlated Phenotypic Alterations in Cells Isolated From Human Degenerated Intervertebral Discs With Contained Hernias.<\/a><br><small><strong>Authors:<\/strong> Molinos M, Cunha C, Almeida CR, Gon\u00e7alves RM, Pereira P, Silva PS, Vaz R, Barbosa MA<\/small><br><small><strong>Published:<\/strong> 2018 Mar 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28546769\/\" target=\"_blank\" rel=\"noopener noreferrer\">Treatment of chronic low back pain - new approaches on the horizon.<\/a><br><small><strong>Authors:<\/strong> Knezevic NN, Mandalia S, Raasch J, Knezevic I, Candido KD<\/small><br><small><strong>Published:<\/strong> 2017<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28471303\/\" target=\"_blank\" rel=\"noopener noreferrer\">Bone Marrow-Derived Mesenchymal Stem Cells as Autologous Therapy in Dogs with Naturally Occurring Intervertebral Disc Disease: Feasibility, Safety, and Preliminary Results.<\/a><br><small><strong>Authors:<\/strong> Steffen F, Smolders LA, Roentgen AM, Bertolo A, Stoyanov J<\/small><br><small><strong>Published:<\/strong> 2017 Nov<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28298159\/\" target=\"_blank\" rel=\"noopener noreferrer\">Biological Behavior of Human Nucleus Pulposus Mesenchymal Stem Cells in Response to Changes in the Acidic Environment During Intervertebral Disc Degeneration.<\/a><br><small><strong>Authors:<\/strong> Liu J, Tao H, Wang H, Dong F, Zhang R, Li J, Ge P, Song P, Zhang H, Xu P, Liu X, Shen C<\/small><br><small><strong>Published:<\/strong> 2017 Jun 15<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28297581\/\" target=\"_blank\" rel=\"noopener noreferrer\">Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration.<\/a><br><small><strong>Authors:<\/strong> Cunha C, Almeida CR, Almeida MI, Silva AM, Molinos M, Lamas S, Pereira CL, Teixeira GQ, Monteiro AT, Santos SG, Gon\u00e7alves RM, Barbosa MA<\/small><br><small><strong>Published:<\/strong> 2017 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28180980\/\" target=\"_blank\" rel=\"noopener noreferrer\">Myofibroblast in the ligamentum flavum hypertrophic activity.<\/a><br><small><strong>Authors:<\/strong> Hur JW, Bae T, Ye S, Kim JH, Lee S, Kim K, Lee SH, Kim JS, Lee JB, Cho TH, Park JY, Hur JK<\/small><br><small><strong>Published:<\/strong> 2017 Aug<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27507100\/\" target=\"_blank\" rel=\"noopener noreferrer\">Biomimetic nucleus pulposus scaffold created from bovine caudal intervertebral disc tissue utilizing an optimal decellularization procedure.<\/a><br><small><strong>Authors:<\/strong> Fernandez C, Marionneaux A, Gill S, Mercuri J<\/small><br><small><strong>Published:<\/strong> 2016 Dec<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27585696\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study.<\/a><br><small><strong>Authors:<\/strong> Elabd C, Centeno CJ, Schultz JR, Lutz G, Ichim T, Silva FJ<\/small><br><small><strong>Published:<\/strong> 2016 Sep 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27527664\/\" target=\"_blank\" rel=\"noopener noreferrer\">Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.<\/a><br><small><strong>Authors:<\/strong> Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H<\/small><br><small><strong>Published:<\/strong> 2016 Aug 16<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27066769\/\" target=\"_blank\" rel=\"noopener noreferrer\">Concise Review: Stem Cell Trials Using Companion Animal Disease Models.<\/a><br><small><strong>Authors:<\/strong> Hoffman AM, Dow SW<\/small><br><small><strong>Published:<\/strong> 2016 Jul<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27051350\/\" target=\"_blank\" rel=\"noopener noreferrer\">Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs.<\/a><br><small><strong>Authors:<\/strong> Kim Y, Lee SH, Kim WH, Kweon OK<\/small><br><small><strong>Published:<\/strong> 2016 Mar<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26953666\/\" target=\"_blank\" rel=\"noopener noreferrer\">Cell-Based Therapies for Lumbar Discogenic Low Back Pain: Systematic Review and Single-Arm Meta-analysis.<\/a><br><small><strong>Authors:<\/strong> Wu T, Song HX, Dong Y, Li JH<\/small><br><small><strong>Published:<\/strong> 2018 Jan 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26933821\/\" target=\"_blank\" rel=\"noopener noreferrer\">Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration.<\/a><br><small><strong>Authors:<\/strong> Lin X, Fang X, Wang Q, Hu Z, Chen K, Shan Z, Chen S, Wang J, Mo J, Ma J, Xu W, Qin A, Fan S<\/small><br><small><strong>Published:<\/strong> 2016 Mar 15<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26649308\/\" target=\"_blank\" rel=\"noopener noreferrer\">Global Gene Expression Profiling and Alternative Splicing Events during the Chondrogenic Differentiation of Human Cartilage Endplate-Derived Stem Cells.<\/a><br><small><strong>Authors:<\/strong> Shang J, Fan X, Shangguan L, Liu H, Zhou Y<\/small><br><small><strong>Published:<\/strong> 2015<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26505389\/\" target=\"_blank\" rel=\"noopener noreferrer\">Determination of the potential of induced pluripotent stem cells to differentiate into mouse nucleus pulposus cells in vitro.<\/a><br><small><strong>Authors:<\/strong> Liu K, Chen Z, Luo XW, Song GQ, Wang P, Li XD, Zhao M, Han XW, Bai YG, Yang ZL, Feng G<\/small><br><small><strong>Published:<\/strong> 2015 Oct 16<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26242341\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intraspinal Transplantation of Autologous Neurogenically-Induced Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Paraplegic Dogs without Deep Pain Perception Secondary to Intervertebral Disk Disease.<\/a><br><small><strong>Authors:<\/strong> Besalti O, Can P, Akpinar E, Aktas Z, Elcin AE, Elcin YM<\/small><br><small><strong>Published:<\/strong> 2015<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25741710\/\" target=\"_blank\" rel=\"noopener noreferrer\">Potential and limitations of intervertebral disc endogenous repair.<\/a><br><small><strong>Authors:<\/strong> Li Z, Peroglio M, Alini M, Grad S<\/small><br><small><strong>Published:<\/strong> 2015<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25682272\/\" target=\"_blank\" rel=\"noopener noreferrer\">Adverse effects of stromal vascular fraction during regenerative treatment of the intervertebral disc: observations in a goat model.<\/a><br><small><strong>Authors:<\/strong> Detiger SE, Helder MN, Smit TH, Hoogendoorn RJ<\/small><br><small><strong>Published:<\/strong> 2015 Sep<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25542789\/\" target=\"_blank\" rel=\"noopener noreferrer\">A combined biomaterial and cellular approach for annulus fibrosus rupture repair.<\/a><br><small><strong>Authors:<\/strong> Pirvu T, Blanquer SB, Benneker LM, Grijpma DW, Richards RG, Alini M, Eglin D, Grad S, Li Z<\/small><br><small><strong>Published:<\/strong> 2015 Feb<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25429703\/\" target=\"_blank\" rel=\"noopener noreferrer\">Intervertebral Disc Engineering through Exploiting Mesenchymal Stem Cells: Progress and Perspective.<\/a><br><small><strong>Authors:<\/strong> Tam WK, Cheung KM, Leung VY<\/small><br><small><strong>Published:<\/strong> 2016<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25384834\/\" target=\"_blank\" rel=\"noopener noreferrer\">Duration of TGF-\u03b23 Exposure Impacts the Chondrogenic Maturation of Human MSCs in Photocrosslinked Carboxymethylcellulose Hydrogels.<\/a><br><small><strong>Authors:<\/strong> Gupta MS, Nicoll SB<\/small><br><small><strong>Published:<\/strong> 2015 May<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25376622\/\" target=\"_blank\" rel=\"noopener noreferrer\">Enhancing cell migration in shape-memory alginate-collagen composite scaffolds: In\u00a0vitro and ex vivo assessment for intervertebral disc repair.<\/a><br><small><strong>Authors:<\/strong> Guillaume O, Naqvi SM, Lennon K, Buckley CT<\/small><br><small><strong>Published:<\/strong> 2015 Apr<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25203751\/\" target=\"_blank\" rel=\"noopener noreferrer\">Gene expression profile analysis of human mesenchymal stem cells from herniated and degenerated intervertebral discs reveals different expression of osteopontin.<\/a><br><small><strong>Authors:<\/strong> Marfia G, Navone SE, Di Vito C, Tabano S, Giammattei L, Di Cristofori A, Gualtierotti R, Tremolada C, Zavanone M, Caroli M, Torchia F, Miozzo M, Rampini P, Riboni L, Campanella R<\/small><br><small><strong>Published:<\/strong> 2015 Feb 1<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25024024\/\" target=\"_blank\" rel=\"noopener noreferrer\">Molecular basis of intervertebral disc degeneration and herniations: what are the important translational questions?<\/a><br><small><strong>Authors:<\/strong> Kadow T, Sowa G, Vo N, Kang JD<\/small><br><small><strong>Published:<\/strong> 2015 Jun<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24405888\/\" target=\"_blank\" rel=\"noopener noreferrer\">Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system.<\/a><br><small><strong>Authors:<\/strong> Chon BH, Lee EJ, Jing L, Setton LA, Chen J<\/small><br><small><strong>Published:<\/strong> 2013 Oct 2<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24234817\/\" target=\"_blank\" rel=\"noopener noreferrer\">Stem cell regeneration of degenerated intervertebral discs: current status (update).<\/a><br><small><strong>Authors:<\/strong> Gilbert HT, Hoyland JA, Richardson SM<\/small><br><small><strong>Published:<\/strong> 2013 Dec<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23951558\/\" target=\"_blank\" rel=\"noopener noreferrer\">Stemming the Degeneration: IVD Stem Cells and Stem Cell Regenerative Therapy for Degenerative Disc Disease.<\/a><br><small><strong>Authors:<\/strong> Sivakamasundari V, Lufkin T<\/small><br><small><strong>Published:<\/strong> 2013<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23918585\/\" target=\"_blank\" rel=\"noopener noreferrer\">Familial occurrence of pulmonary embolism after intravenous, adipose tissue-derived stem cell therapy.<\/a><br><small><strong>Authors:<\/strong> Jung JW, Kwon M, Choi JC, Shin JW, Park IW, Choi BW, Kim JY<\/small><br><small><strong>Published:<\/strong> 2013 Sep<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23896572\/\" target=\"_blank\" rel=\"noopener noreferrer\">Neuroprotective effects of mesenchymal stem cells on spinal motoneurons following ventral root axotomy: synapse stability and axonal regeneration.<\/a><br><small><strong>Authors:<\/strong> Spejo AB, Carvalho JL, Goes AM, Oliveira AL<\/small><br><small><strong>Published:<\/strong> 2013 Oct 10<\/small><\/li><li style=\"margin-bottom:15px;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23621741\/\" target=\"_blank\" rel=\"noopener noreferrer\">Construction of a tissue-engineered annulus fibrosus.<\/a><br><small><strong>Authors:<\/strong> Cho H, Park SH, Park K, Shim JW, Huang J, Smith R, Elder S, Min BH, Hasty KA<\/small><br><small><strong>Published:<\/strong> 2013 Jul<\/small><\/li><\/ul><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":18,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_joinchat":[],"footnotes":""},"class_list":["post-807","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/pages\/807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=807"}],"version-history":[{"count":2,"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/pages\/807\/revisions"}],"predecessor-version":[{"id":822,"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/pages\/807\/revisions\/822"}],"up":[{"embeddable":true,"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=\/wp\/v2\/pages\/18"}],"wp:attachment":[{"href":"https:\/\/www.ozonoterapia-peru.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}