Estudios científicos
Estudios clinicos en pacientes con hernia discal tratados con ozono
- CT-guided transforaminal versus C-arm-guided intradiscal ozone injection for cervical disc herniation: a comparative cohort study.
Authors: Yang MJ, Qiong X, Yang H, Qiu Z, He L, Yang H, Xu X, Al-Goshae HAA
Published: 2026 - Pain catastrophizing and postoperative satisfaction in cervical disc herniation: a 6-month prospective cohort study.
Authors: Mao-Jiang Y, Xian Q, Han-Feng Y, Xiao-Xue X, Al-Goshae HAA
Published: 2026 Feb 10 - Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.
Authors: Wang H, Xu L, Deng J, Qiu X, Dong C, Hu Y, Li Q, Mei T, Chen S, Wu Y, Miao L, Huang F, Huang M, Cheng Y, Sun J, Yu L
Published: 2026 Jan 23 - How Safe Are Oxygen-Ozone Therapy Procedures for Spine Disc Herniation? The SIOOT Protocols for Treating Spine Disorders.
Authors: Franzini M, Chirumbolo S, Vaiano F, Valdenassi L, Giannetti F, Chierchia M, Tirelli U, Bonacina P, Poggi G, Langella A, Pieracci EM, Giannetti C, Giannetti RA
Published: 2025 Dec 1 - Computed tomography-guided oxygen-ozone injection for the treatment of lumbar disc herniation complicated with lumbar spinal stenosis.
Authors: Chen J, Song Z, Zheng K, Yao Z, Wang M, Li G, Xu J, Gu Y, Deng S, Chen Q, Xu Y
Published: 2026 Sep 1 - Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain-a systematic review and meta-analysis.
Authors: Cao D, Li X, Zhang X, Tian Y, Gu W, Zhu X, Yuan H
Published: 2025 - Chemonucleolysis for Lumbar Disc Herniation: History and Current State of the Technology.
Authors: Deer TR, Macadaeg KE, Kim KD, Copenhaver DJ, Cheng BC, Patel A, Vaccaro A, Candido KD, Gupta PB, Beall DP
Published: 2025 - Efficacy and safety of low-temperature plasma radiofrequency ablation combined with ozone injection versus triple therapy including collagenase for cervical disc herniation: a randomized controlled trial.
Authors: Yang Y, Gao Z, Zhang Y, Fang Q, Liu J, Zhao Y, Wu Z
Published: 2026 Apr - Comparison between paravertebral injections of ozone and epidural injections of corticosteroids used in the treatment of lumbosacral pain: scoping review.
Authors: Arias-Vázquez PI, Castillo-Avila RG, Quezada-González R, Hernández-Gil K, Legorreta-Ramírez BG, Ramírez-Wakamatzu MA
Published: 2026 Jun 1 - Efficacy and safety of CT-guided oxygen-ozone (O(2)-O(3)) therapy for low back pain: a retrospective single-center study.
Authors: Bellelli A, D'Andrea V, Pileri M, Beomonte Zobel B
Published: 2025 Nov - Pain Relief, Disability, and Hospital Costs After Intradiscal Ozone Treatment or Microdiscectomy for Lumbar Disc Herniation: A 24-Month Real-World Prospective Study.
Authors: Bisshopp S, Linertová R, Caramés MA, Szolna A, Jorge IJ, Navarro M, Melchiorsen B, Rodríguez-Díaz B, González-Martín JM, Clavo B
Published: 2025 Jun 26 - Steroid versus steroid plus ozone during posterior epiduroscopy in the treatment of lumbar herniated disc: results of a 1-year follow-up study.
Authors: Bayram D, Aliyev D, Aşık İ
Published: 2025 Jun 9 - Adverse effects following some practices of ozone therapy for disc herniation. Critical comments.
Authors: Franzini M, Valdenassi L, Vaiano F, Chirumbolo S
Published: 2025 Jun - Various gases for the treatment of neuropathic pain: mechanisms, current status, and future perspectives.
Authors: Liu Y, Shen T, Li Q, Yu X, Liu Y, Zhou C, Han J, Zhu Y
Published: 2025 Dec 1 - Ozone therapy-associated pneumoperitoneum in a patient with low back pain: A case report.
Authors: Shamohammadi M, Mazraeh M, Tayebi A, Olamaeian F, Moallem HH
Published: 2025 May - How Effective is Ozone Therapy in Treatment of Lumbar Disc Disease: a Systematic Review of Prospective Studies.
Authors: Kumar V, Ifthekar S, Raj V, Varikasuvu SR, Jain A, Vatkar A, Kandwal P, Barik S
Published: 2024 Dec - Developments and clinical experiences in collagenase chemonucleolysis for lumbar disc herniation: a narrative review.
Authors: Zhang H, Zhang C, Li L, Hu ML, Zhao JN, Zheng Z, Ding WF
Published: 2024 - Cerebral gas embolism and multifocal ischemic stroke during oxygen-ozone therapy: a case report.
Authors: Khosravi S, Mirzaasgari Z
Published: 2024 - Effectiveness of ozone nucleolysis in alleviating pain and enhancing function in lumbar sciatica due to disc herniation: a minimally invasive approach.
Authors: Kharrat A, Elmounedi N, Tmar MA, Bahloul W, Guidara AR, Lajmi A, Sahnoun N, Trigui M, Ellouz Z, Keskes H
Published: 2025 Jan - Effects of Ozone Disc Nucleolysis in Management of Herniated Lumbar Intervertebral Disc: A Retrospective Single-Center Study of 149 Patients.
Authors: Atcı IB, Turk O, Demirel N, Demir H, Gurcan Atci A, Karaoglu AC, Abut Y, Yilmaz H
Published: 2024 Jul 17 - Effectiveness of intradiscal ozone injections for treating pain following herniated lumbar disc: A systematic review and meta-analysis.
Authors: Chang MC, Choo YJ, Denis I, Mares C, Majdalani C, Yang S
Published: 2024 - Ozone Disc Nucleolysis for Cervical Intervertebral Disc Herniation: A Systematic Review and Meta-Analysis.
Authors: Ghatge SB, Asarkar A, Warghade SS, Shirsat S, Deb A
Published: 2024 May - Combined ozone therapy and acupoint injection alleviate the postoperative pain of lumbar disc herniation.
Authors: Qing L, Paerhate S, Liu C, Ni J
Published: 2024 Nov - Clinical Outcome for Lumbar Disc Herniation Treatment with Intradiscal Oxygen-ozone Therapy.
Authors: Yadav RK, Sherpa T, Hamal PK, Pokhrel N, Thakur JP, Amatya SP, Piya R
Published: 2024 Mar 31 - Oxygen-Ozone Therapy of Musculoskeletal Neck Pain: A Review.
Authors: Jandura J, Vajda M, Cech M, Ryska P
Published: 2024 Mar 21 - US/CT fusion imaging and virtual navigation to guide lumbar intradiscal oxygen-ozone therapy: a pilot study.
Authors: Albano D, Messina C, Gitto S, Fusco S, Sconfienza LM, Bellelli A
Published: 2024 Jun - Intramuscular paravertebral oxygen-ozone therapy for chronic neck pain and low back pain: evaluation of 6-month clinical outcomes.
Authors: Latini E, Nusca SM, Curci ER, Boaretto D, Santoboni F, Trischitta D, Vetrano M, Vulpiani MC
Published: 2024 Jan-Mar - Alpha-Lipoic Acid, Palmitoylethanolamide, Myrrh, and Oxygen-Ozone Therapy Improve Pharmacological Therapy in Acute Painful Lumbosacral Radiculopathy due to Herniated Disc.
Authors: Latini E, Bonasia G, Petroselli L, Mazzola M, Musa F, Santoboni F, Trischitta D, Sveva MN, Vetrano M, Vulpiani MC
Published: 2023 Jul - Randomized single-blinded prospective comparison between ozone therapy and electroacupuncture for canine thoracolumbar disk disease.
Authors: Sumida JM, Matera JM, Hayashi AM
Published: 2023 Aug - Sex life and low back pain: The impact of intradiscal ozone therapy in patients with herniated lumbar disc.
Authors: Somma F, Negro A, Tortora M, Gemini L, Pace G, Fasano F, Piscitelli V, Sicignano C, Prudente M, Falco A, Villa A, Lugarà M, Pezzullo G, D'Agostino V, Gatta G
Published: 2025 Oct - Ozone disc nucleolysis in the management of herniated lumbar intervertebral disc: A retrospective analysis.
Authors: Ghatge SB, Shah RP, Surya N, Sankhala S, Unadkat CJ, Khan GM, Modi DB
Published: 2023 Jan-Mar - The Use of Medical Ozone in Chronic Intervertebral Disc Degeneration Can Be an Etiological and Conservative Treatment.
Authors: Grangeat AM, Erario MLA
Published: 2023 Mar 31 - Radiation Exposure during Fluoroscopy-Guided Ozone Chemonucleolysis for Lumbar Disc Herniation.
Authors: Leoni MLG, Vitali S, Micheli F, Mercieri M, Varrassi G, Casale R, Occhigrossi F, Giordano C
Published: 2022 Dec 14 - Clinical treatment of lumbar disc herniation.
Authors: Zhang W, Wang Z, Yin J, Bai Y, Qiu F, Zhang H, Zhang H, Wang B, Zhang F, Ji S, Yuan M, Zhao H, Yang H
Published: 2022 - COVID-19, intradiscal ozone therapy and back pain: a correspondence.
Authors: Mungmunpuntipantip R, Wiwanitkit V
Published: 2022 Oct - Clinical utility of ozone therapy and hyperbaric oxygen therapy in degenerative disc disease.
Authors: Re K, Gandhi J, Liang R, Patel S, Joshi G, Smith NL, Reid I, Khan SA
Published: 2023 Jan-Mar - Comparative effect of transforaminal injection of Magnesium sulphate versus Ozone on oxidative stress biomarkers in lumbar disc related radicular pain.
Authors: Fathy W, Hussein M, Ibrahim RE, Abdel-Aziz MM, Adel S, Soliman SH, Elmoutaz H, Abdelkader M
Published: 2022 Aug 8 - Ozone disc nucleolysis in cervical intervertebral disc herniation: A nonrandomized prospective analysis in 246 patients.
Authors: Ghatge SB, Shah RP, Surya N, Sankhala S, Unadkat CJ, Khan GM, Modi DB
Published: 2022 Apr-Jun - Oxygen-Ozone Therapy Associated with Alpha Lipoic Acid Plus Palmitoylethanolamide and Myrrh versus Ozone Therapy in the Combined Treatment of Sciatic Pain Due to Herniated Discs: Observational Study on 318 Patients.
Authors: Bonetti M, Lauritano D, Ottaviani GM, Fontana A, Zambello A, Della Gatta L, Muto M, Carinci F
Published: 2022 May 7 - COVID-19 and low back pain: previous infections lengthen recovery time after intradiscal ozone therapy in patients with herniated lumbar disc.
Authors: Somma F, Negro A, D'Agostino V, Piscitelli V, Pace G, Tortora M, Tortora F, Gatta G, Caranci F
Published: 2022 Jun - Mycobacterium tuberculosis Infection of the Spine Secondary to Oxygen - Ozone Therapy for Prolapse Intervertebral Disc: A Scoping Review.
Authors: Salaria AK, Dhatt SS, Kumar V, Neradi D, Sodavarapu P, Kumar N
Published: 2021 Jun - Intradiscal ozone therapy: fluoroscopic guidance reduces operative time in comparison with CT guidance in patients with lumbar disc herniation.
Authors: Somma F, Gatta G, Negro A, Tortora M, Rea G, Tamburrini S, Pace G, La Tessa GME, Caranci F, d'Agostino V
Published: 2022 May - Radiation exposure and clinical outcome in patients undergoing percutaneous intradiscal ozone therapy for disc herniation: Fluoroscopic versus conventional CT guidance.
Authors: Somma F, D'Agostino V, Negro A, Piscitelli V, Tamburrini S, Sicignano C, Fasano F, Peluso S, Villa A, Pace G, Sarti G, La Tessa GME, Pezzullo G, Gatta G, Caranci F
Published: 2022 - Metanalysis on the effectiveness of low back pain treatment with oxygen-ozone mixture: Comparison between image-guided and non-image-guided injection techniques.
Authors: Rimeika G, Saba L, Arthimulam G, Della Gatta L, Davidovic K, Bonetti M, Franco D, Russo C, Muto M
Published: 2021 - Intradiscal oxygen-ozone chemonucleolysis versus microdiscectomy for lumbar disc herniation radiculopathy: a non-inferiority randomized control trial.
Authors: Kelekis A, Bonaldi G, Cianfoni A, Filippiadis D, Scarone P, Bernucci C, Hooper DM, Benhabib H, Murphy K, Buric J
Published: 2022 Jun - Periradicular corticosteroid infiltration for radicular pain - comparison of Diprophos and Depomedrone and ozone effects.
Authors: Krahulik D, Vaverka M, Hrabalek L, Pohlodek D, Jablonsky J, Valosek J, Zapletalova J
Published: 2023 Mar - Oxygen-ozone therapy for the treatment of low back pain: a systematic review of randomized controlled trials.
Authors: Sconza C, Leonardi G, Kon E, Respizzi S, Massazza G, Marcacci M, Di Matteo B
Published: 2021 Oct - Intradiscal oxygen-ozone therapy for the treatment of symptomatic lumbar disc herniation: A preliminary study.
Authors: Simon C, Le Corroller T, Pauly V, Creze M, Champsaur P, Guenoun D
Published: 2022 Mar - Ozone as Modulator of Resorption and Inflammatory Response in Extruded Nucleus Pulposus Herniation. Revising Concepts.
Authors: Erario MLÁ, Croce E, Moviglia Brandolino MT, Moviglia G, Grangeat AM
Published: 2021 Sep 14 - O(2)-O(3) chemodiscolysis: How much, how long? Retrospective outcome evaluation of different treatment sessions in partially-responder patients.
Authors: Bruno F, Carboni N, Palumbo P, Arrigoni F, Varrassi M, Izzo A, Catallo N, Di Cesare E, Masciocchi C, Splendiani A, Giovagnoni A, Barile A
Published: 2022 Aug