Unidad de Terapia Regenerativa Tisular – Centro Medico Clinica Alemana

Estudios científicos

1. Li, T, Du, W, Ding, Z, Liu, J, Ding, Y. Percutaneous endoscopic lumbar discectomy combined with platelet-rich plasma injection for lumbar disc herniation: analysis of clinical and imaging outcomes. BMC Musculoskelet Disord. 2024;25 (1):328. doi: 10.1186/s12891-024-07444-8. PubMed PMID:38658984 .
2. Guerrero-Molina, AL, Cruz-Álvarez, MG, Tenopala-Villegas, S. [Bibliographic review of the efficacy of platelet-rich plasma treatment in lumbar disc herniation]. Acta Ortop Mex. 2023;37 (5):290-295. . PubMed PMID:38382454 .
3. Hasegawa, T, Akeda, K, Yamada, J, Kawaguchi, K, Takegami, N, Fujiwara, T et al.. Regenerative effects of platelet-rich plasma releasate injection in rabbit discs degenerated by intradiscal injection of condoliase. Arthritis Res Ther. 2023;25 (1):216. doi: 10.1186/s13075-023-03200-w. PubMed PMID:37941067 PubMed Central PMC10631205.
4. Zhang, L, Zhang, C, Song, D, Chen, G, Liu, L. Combination of percutaneous endoscopic lumbar discectomy and platelet-rich plasma hydrogel injection for the treatment of lumbar disc herniation. J Orthop Surg Res. 2023;18 (1):609. doi: 10.1186/s13018-023-04093-w. PubMed PMID:37605261 PubMed Central PMC10440935.
5. Wongjarupong, A, Pairuchvej, S, Laohapornsvan, P, Kotheeranurak, V, Jitpakdee, K, Yeekian, C et al.. "Platelet-Rich Plasma" epidural injection an emerging strategy in lumbar disc herniation: a Randomized Controlled Trial. BMC Musculoskelet Disord. 2023;24 (1):335. doi: 10.1186/s12891-023-06429-3. PubMed PMID:37118707 PubMed Central PMC10141936.
6. Kawabata, S, Hachiya, K, Nagai, S, Takeda, H, Rashid, MZM, Ikeda, D et al.. Autologous Platelet-Rich Plasma Administration on the Intervertebral Disc in Low Back Pain Patients with Modic Type 1 Change: Report of Two Cases. Medicina (Kaunas). 2023;59 (1):. doi: 10.3390/medicina59010112. PubMed PMID:36676735 PubMed Central PMC9863543.
7. Le, VT, Nguyen Dao, LT, Nguyen, AM. Transforaminal injection of autologous platelet-rich plasma for lumbar disc herniation: A single-center prospective study in Vietnam. Asian J Surg. 2023;46 (1):438-443. doi: 10.1016/j.asjsur.2022.05.047. PubMed PMID:35637114 .
8. Lutz, C, Cheng, J, Prysak, M, Zukofsky, T, Rothman, R, Lutz, G et al.. Clinical outcomes following intradiscal injections of higher-concentration platelet-rich plasma in patients with chronic lumbar discogenic pain. Int Orthop. 2022;46 (6):1381-1385. doi: 10.1007/s00264-022-05389-y. PubMed PMID:35344055 PubMed Central PMC9117340.
9. Jiang, Y, Zuo, R, Yuan, S, Li, J, Liu, C, Zhang, J et al.. Transforaminal Endoscopic Lumbar Discectomy with versus without Platelet-Rich Plasma Injection for Lumbar Disc Herniation: A Prospective Cohort Study. Pain Res Manag. 2022;2022 :6181478. doi: 10.1155/2022/6181478. PubMed PMID:35296040 PubMed Central PMC8920626.
10. Schneider, BJ, Hunt, C, Conger, A, Qu, W, Maus, TP, Vorobeychik, Y et al.. The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review. Spine J. 2022;22 (2):226-237. doi: 10.1016/j.spinee.2021.07.015. PubMed PMID:34352363 .
11. Xu, Z, Wu, S, Li, X, Liu, C, Fan, S, Ma, C et al.. Ultrasound-Guided Transforaminal Injections of Platelet-Rich Plasma Compared with Steroid in Lumbar Disc Herniation: A Prospective, Randomized, Controlled Study. Neural Plast. 2021;2021 :5558138. doi: 10.1155/2021/5558138. PubMed PMID:34135954 PubMed Central PMC8175124.
12. Jain, D, Goyal, T, Verma, N, Paswan, AK, Dubey, RK. Intradiscal Platelet-Rich Plasma Injection for Discogenic Low Back Pain and Correlation with Platelet Concentration: A Prospective Clinical Trial. Pain Med. 2020;21 (11):2719-2725. doi: 10.1093/pm/pnaa254. PubMed PMID:32869064 .
13. Knezevic, NN, Mandalia, S, Raasch, J, Knezevic, I, Candido, KD. Treatment of chronic low back pain - new approaches on the horizon. J Pain Res. 2017;10 :1111-1123. doi: 10.2147/JPR.S132769. PubMed PMID:28546769 PubMed Central PMC5436786.
14. Monfett, M, Harrison, J, Boachie-Adjei, K, Lutz, G. Intradiscal platelet-rich plasma (PRP) injections for discogenic low back pain: an update. Int Orthop. 2016;40 (6):1321-8. doi: 10.1007/s00264-016-3178-3. PubMed PMID:27073034 .
15. Hoggatt, J. Hot ortho-biologic topics at AAOS 2011†: platelet-rich plasma and related growth factors generate excitement. BioDrugs. 2011;25 (3):197-202. doi: 10.2165/11592710-000000000-00000. PubMed PMID:21627344 .
16. Chen, WH, Liu, HY, Lo, WC, Wu, SC, Chi, CH, Chang, HY et al.. Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma. Biomaterials. 2009;30 (29):5523-33. doi: 10.1016/j.biomaterials.2009.07.019. PubMed PMID:19646749 .
17. Nagae, M, Ikeda, T, Mikami, Y, Hase, H, Ozawa, H, Matsuda, K et al.. Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres. Tissue Eng. 2007;13 (1):147-58. doi: 10.1089/ten.2006.0042. PubMed PMID:17518588 .