Estudios científicos
- Single-Step Extrusion Printing of Microgrooved Annulus Fibrosus Scaffolds via Patterned Nozzles.
Authors: Kluser N, Alig GU, Sprecher C, Woods X, Grad S, Alini M, Häckel S, Albers CE, Eglin D, Narayanan R, Vernengo AJ
Published: 2026 Mar 11 - TIE2-positive cells in the nucleus pulposus with a purpose: the who, what and why.
Authors: Schol J, Ambrosio L, Ruiz-Fernandez C, Schlagenhof L, Voskamp C, Laagland LT, Matsushita E, Soma H, Warita T, Vadalà G, Tryfonidou MA, Gantenbein B, Sakai D
Published: 2026 Mar 2 - Aligned nanofibrous patch for sustained nicardipine delivery and enhanced chondrogenic differentiation in annulus fibrosus repair.
Authors: Deekshika S, Sumi VS, Vellara JF, Cr R, Nair M
Published: 2025 Oct 29 - Exosome Therapy: A Promising Avenue for Treating Intervertebral Disc Degeneration.
Authors: Bhat S, Kannan S, Kolkundkar UK, Seetharam RN
Published: 2025 Oct - 14. Discogenic Low Back Pain.
Authors: van Os WKM, Alvarez-Jimenez R, Cohen SP, Stojanovic MP, Ruiz-Lopez R, Van Zundert J, Kallewaard JW
Published: 2025 Sep - Advances in Annulus Fibrosus Repair: Hybrid Scaffolds and Fabrication Techniques for Regeneration.
Authors: ADaLi ML, Nie MD, Zhang Q, Li YD, Yang QQ, Fang F, Cheng CK
Published: 2025 Jun 5 - Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models.
Authors: Yang S, Soheilmoghaddam F, Pivonka P, Li J, Rudd S, Yeo T, Tu J, Zhu Y, Cooper-White JJ
Published: 2025 Sep - Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors.
Authors: Li ZP, Li H, Ruan YH, Wang P, Zhu MT, Fu WP, Wang RB, Tang XD, Zhang Q, Li SL, Yin H, Li CJ, Tian YG, Han RN, Wang YB, Zhang CJ
Published: 2025 Apr 26 - A self-powered sandwich-structured scaffold with dual-electroactive properties to regenerate damaged intervertebral discs after discectomy.
Authors: Wang J, Huang L, Guo T, Liu Z, Xu H, Yang H, Liu L, Feng G, Zhang L
Published: 2025 May 7 - Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Authors: Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M
Published: 2025 Apr 1 - Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.
Authors: Wang M, He Z, Wang A, Sun S, Li J, Liu F, Li C, Yang C, Lei J, Yu Y, Ma S, Wang S, Zhang W, Yu Z, Liu GH, Qu J
Published: 2025 Aug 7 - Pyroptosis: candidate key targets for mesenchymal stem cell-derived exosomes for the treatment of bone-related diseases.
Authors: Li H, Zhang P, Lin M, Li K, Zhang C, He X, Gao K
Published: 2025 Feb 12 - Bone Marrow Aspirate Concentrate Combined with Ultra-Purified Alginate Bioresorbable Gel Enhances Intervertebral Disc Repair in a Canine Model: A Preclinical Proof-of-Concept Study.
Authors: Ukeba D, Ishikawa Y, Yamada K, Ohnishi T, Tachi H, Tha KK, Iwasaki N, Sudo H
Published: 2024 Jun 5 - Exosomes for the Management of Low Back Pain: A Review of Current Clinical Evidence.
Authors: Gupta A
Published: 2024 Apr - Remarkable recovery of lower extremity motor impairment in degenerative disc disease after percutaneous laser disc decompression combined with umbilical cord-derived mesenchymal stem cells implantation: A case report.
Authors: Rahyussalim AJ, Andar AA, Canintika AF, Putri DA, Kurniawati T
Published: 2024 May - Menstrual blood-derived mesenchymal stem cells combined with collagen I gel as a regenerative therapeutic strategy for degenerated disc after discectomy in rats.
Authors: Yu L, Wu H, Zeng S, Hu X, Wu Y, Zhou J, Yuan L, Zhang Q, Xiang C, Feng Z
Published: 2024 Mar 13 - Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus-like cell phenotype.
Authors: Peredo AP, Tsinman TK, Bonnevie ED, Jiang X, Smith HE, Gullbrand SE, Dyment NA, Mauck RL
Published: 2024 Mar - Future of low back pain: unravelling IVD components and MSCs' potential.
Authors: Leão Monteiro R
Published: 2024 Jan 16 - Percutaneous laser disc decompression combined with secretome of umbilical cord-derived mesenchymal stem cells in a patient with spinal cord injury: A case report.
Authors: Rahyussalim AJ, Priyono AH, Budhy F, Muntaha M, Ramadhani R, Canintika AF
Published: 2024 Jan - Biological Therapeutic Modalities for Intervertebral Disc Diseases: An Orthoregeneration Network (ON) Foundation Review.
Authors: Mizuno S, Vadala G, Kang JD
Published: 2024 Mar - Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration.
Authors: Hu X, Tian X, Yang C, Ling F, Liu H, Zhu X, Pei M, Yang H, Liu T, Xu Y, He F
Published: 2023 Dec - Signaling Mechanisms of Stem Cell Therapy for Intervertebral Disc Degeneration.
Authors: Du X, Liang K, Ding S, Shi H
Published: 2023 Sep 6 - Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Authors: Wang P, Yang C, Lu J, Ren Y, Goltzman D, Miao D
Published: 2023 May - Exosome-mediated Repair of Intervertebral Disc Degeneration: The Potential Role of miRNAs.
Authors: Wang HS, Lin S, Yu HM
Published: 2024 - The Use of Medical Ozone in Chronic Intervertebral Disc Degeneration Can Be an Etiological and Conservative Treatment.
Authors: Grangeat AM, Erario MLA
Published: 2023 Mar 31 - Pain Relief After Allogenic Stem Cell Disc Therapy.
Authors: Lewandrowski KU, Dowling A, Vera JC, Leon JFR, Telfeian AE, Lorio MP
Published: 2023 Mar - Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre, prospective, double-blind randomised controlled trial.
Authors: Sudo H, Miyakoshi T, Watanabe Y, Ito YM, Kahata K, Tha KK, Yokota N, Kato H, Terada T, Iwasaki N, Arato T, Sato N, Isoe T
Published: 2023 Feb 2 - Comprehensive narrative review on the analysis of outcomes from cell transplantation clinical trials for discogenic low back pain.
Authors: Schol J, Sakai D
Published: 2023 Mar - Gene expression profiling in nucleus pulposus of human ruptured lumbar disc herniation.
Authors: Li X, Shen X, Wang Z, Jiang H, Ma Z, Yu P, Yu Z, Qian X, Liu J
Published: 2022 - Decellularized extracellular matrix-based scaffold and hypoxic priming: A promising combination to improve the phenotype of degenerate intervertebral disc cells.
Authors: Penolazzi L, Lambertini E, D'Agostino S, Pozzobon M, Notarangelo MP, Greco P, De Bonis P, Nastruzzi C, Piva R
Published: 2022 Jul 15 - Treatment of Intervertebral Disc Degeneration.
Authors: Xin J, Wang Y, Zheng Z, Wang S, Na S, Zhang S
Published: 2022 Jul - Intradiscal Injection of Autologous Discogenic Cells in Patients with Discectomy: A Prospective Clinical Study of Its Safety and Feasibility.
Authors: Xuan A, Ruan D, Wang C, He Q, Wang D, Hou L, Zhang C, Li C, Ji W, Wen T, Xu C, Zhu Z
Published: 2022 May 27 - Direct Reprogramming and Induction of Human Dermal Fibroblasts to Differentiate into iPS-Derived Nucleus Pulposus-like Cells in 3D Culture.
Authors: Seki S, Iwasaki M, Makino H, Yahara Y, Miyazaki Y, Kamei K, Futakawa H, Nogami M, Tran Canh Tung N, Hirokawa T, Tsuji M, Kawaguchi Y
Published: 2022 Apr 6 - Clinical Development of Regenerative Medicine Targeted for Intervertebral Disc Disease.
Authors: Sakai D, Schol J, Watanabe M
Published: 2022 Feb 10 - Sa12b Improves Biological Activity of Human Degenerative Nucleus Pulposus Mesenchymal Stem Cells in a Severe Acid Environment by Inhibiting Acid-Sensitive Ion Channels.
Authors: Wang Z, Han L, Chen H, Zhang S, Zhang S, Zhang H, Li Y, Tao H, Li J
Published: 2022 - Interleukin-1β More Than Mechanical Loading Induces a Degenerative Phenotype in Human Annulus Fibrosus Cells, Partially Impaired by Anti-Proteolytic Activity of Mesenchymal Stem Cell Secretome.
Authors: Gonçalves RM, Saggese T, Yong Z, Ferreira JR, Ignatius A, Wilke HJ, Neidlinger-Wilke C, Teixeira GQ
Published: 2021 - Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier.
Authors: Widjaja G, Jalil AT, Budi HS, Abdelbasset WK, Efendi S, Suksatan W, Rita RS, Satria AP, Aravindhan S, Saleh MM, Shalaby MN, Yumashev AV
Published: 2022 Apr - Combination of ultra-purified stem cells with an in situ-forming bioresorbable gel enhances intervertebral disc regeneration.
Authors: Ukeba D, Yamada K, Suyama T, Lebl DR, Tsujimoto T, Nonoyama T, Sugino H, Iwasaki N, Watanabe M, Matsuzaki Y, Sudo H
Published: 2022 Feb - Stem Cells and Intervertebral Disc Regeneration Overview-What They Can and Can't Do.
Authors: Vadalà G, Ambrosio L, Russo F, Papalia R, Denaro V
Published: 2021 Apr - The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review.
Authors: Schneider BJ, Hunt C, Conger A, Qu W, Maus TP, Vorobeychik Y, Cheng J, Duszynski B, McCormick ZL
Published: 2022 Feb - Selective Retention of Bone Marrow Stromal Cells with Gelatin Sponge for Repair of Intervertebral Disc Defects after Microendoscopic Discectomy: A Prospective Controlled Study and 2-Year Follow-Up.
Authors: Xu B, Zhang H, Du L, Yuan Q, Zhang K, Xu H, Ma X, Liu Y, Jiang H, Li N
Published: 2021 - Percutaneous transplantation of allogenic bone marrow-derived mesenchymal stem cells for the management of paraplegia secondary to Hansen type I intervertebral disc herniation in a Beagle dog.
Authors: Sharun K, Kumar R, Chandra V, Saxena AC, Pawde AM, Kinjavdekar P, Dhama K, Amarpal, Sharma GT
Published: 2021 Spring - Long-term pre-clinical evaluation of an injectable chitosan nanocellulose hydrogel with encapsulated adipose-derived stem cells in an ovine model for IVD regeneration.
Authors: Schmitt C, Radetzki F, Stirnweiss A, Mendel T, Ludtka C, Friedmann A, Baerthel A, Brehm W, Milosevic J, Meisel HJ, Goehre F, Schwan S
Published: 2021 Jul - Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells.
Authors: Sako K, Sakai D, Nakamura Y, Schol J, Matsushita E, Warita T, Horikita N, Sato M, Watanabe M
Published: 2021 Apr 29 - Exosomes Derived from Human Urine-Derived Stem Cells Inhibit Intervertebral Disc Degeneration by Ameliorating Endoplasmic Reticulum Stress.
Authors: Xiang H, Su W, Wu X, Chen W, Cong W, Yang S, Liu C, Qiu C, Yang SY, Wang Y, Zhang G, Guo Z, Xing D, Chen B
Published: 2020 - Bone Marrow Aspirate Concentrate Combined with in Situ Forming Bioresorbable Gel Enhances Intervertebral Disc Regeneration in Rabbits.
Authors: Ukeba D, Yamada K, Tsujimoto T, Ura K, Nonoyama T, Iwasaki N, Sudo H
Published: 2021 Apr 21 - Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Authors: Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Published: 2021 Apr - Evaluation of Bone Marrow-derived Stem Cells and Adipose-derived Stem Cells Co-cultured on Human Nucleus Pulposus Cells: A Pilot Study.
Authors: Yoon SH, Kim DH, Cho S, Kim KJ
Published: 2020 Oct - Expansion and characterization of cells from surgically removed intervertebral disc fragments in xenogen-free medium.
Authors: Mujawar S, Iyengar K, Nadkarni S, Mulherkar R
Published: 2020 - Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations.
Authors: Agha O, Mueller-Immergluck A, Liu M, Zhang H, Theologis AA, Clark A, Kim HT, Liu X, Feeley BT, Bailey JF
Published: 2020 Jun - Intervertebral Disc Diseases PART 2: A Review of the Current Diagnostic and Treatment Strategies for Intervertebral Disc Disease.
Authors: Wu PH, Kim HS, Jang IT
Published: 2020 Mar 20 - The transcription factors regulating intervertebral disc development.
Authors: Nakamichi R, Asahara H
Published: 2020 Mar - Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs.
Authors: Ukeba D, Sudo H, Tsujimoto T, Ura K, Yamada K, Iwasaki N
Published: 2020 Mar - p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle.
Authors: Che H, Li J, Li Y, Ma C, Liu H, Qin J, Dong J, Zhang Z, Xian CJ, Miao D, Wang L, Ren Y
Published: 2020 Mar 3 - Reduced nucleotomy-induced intervertebral disc disruption through spontaneous spheroid formation by the Low Adhesive Scaffold Collagen (LASCol).
Authors: Takeoka Y, Yurube T, Morimoto K, Kunii S, Kanda Y, Tsujimoto R, Kawakami Y, Fukase N, Takemori T, Omae K, Kakiuchi Y, Miyazaki S, Kakutani K, Takada T, Nishida K, Fukushima M, Kuroda R
Published: 2020 Mar - Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells.
Authors: Torre OM, Mroz V, Benitez ARM, Huang AH, Iatridis JC
Published: 2019 - Comparison of the Efficacy of Surgical Decompression Alone and Combined With Canine Adipose Tissue-Derived Stem Cell Transplantation in Dogs With Acute Thoracolumbar Disk Disease and Spinal Cord Injury.
Authors: Bach FS, Rebelatto CLK, Fracaro L, Senegaglia AC, Fragoso FYI, Daga DR, Brofman PRS, Pimpão CT, Engracia Filho JR, Montiani-Ferreira F, Villanova JA Jr
Published: 2019 - Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response.
Authors: Wangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M, Grad S
Published: 2019 Dec 1 - Combination of stem cells from deciduous teeth and electroacupuncture for therapy in dogs with chronic spinal cord injury: A pilot study.
Authors: Prado C, Fratini P, de Sá Schiavo Matias G, Bocabello RZ, Monteiro J, Dos Santos CJ Jr, Joaquim JGF, Giglio RF, Possebon FS, Sakata SH, Miglino MA
Published: 2019 Apr - Office-Based Mesenchymal Stem Cell Therapy for the Treatment of Musculoskeletal Disease: A Systematic Review of Recent Human Studies.
Authors: Law L, Hunt CL, van Wijnen AJ, Nassr A, Larson AN, Eldrige JS, Mauck WD, Pingree MJ, Yang J, Muir CW, Erwin PJ, Bydon M, Qu W
Published: 2019 Aug 1 - Treatment of Naturally Degenerated Canine Lumbosacral Intervertebral Discs with Autologous Mesenchymal Stromal Cells and Collagen Microcarriers: A Prospective Clinical Study.
Authors: Steffen F, Bertolo A, Affentranger R, Ferguson SJ, Stoyanov J
Published: 2019 Feb - Autogenic mesenchymal stem cells for intervertebral disc regeneration.
Authors: Migliorini F, Rath B, Tingart M, Baroncini A, Quack V, Eschweiler J
Published: 2019 Apr - Impact of Wnt signals on human intervertebral disc cell regeneration.
Authors: Pizzute T, He F, Zhang XB, Pei M
Published: 2018 Dec - In vitro efficacy of silk sericin microparticles and platelet lysate for intervertebral disk regeneration.
Authors: Bari E, Perteghella S, Marrubini G, Sorrenti M, Catenacci L, Tripodo G, Mastrogiacomo M, Mandracchia D, Trapani A, Faragò S, Gaetani P, Torre ML
Published: 2018 Oct 15 - Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model.
Authors: Frauchiger DA, May RD, Bakirci E, Tekari A, Chan SCW, Wöltje M, Benneker LM, Gantenbein B
Published: 2018 Jun 24 - Bone mesenchymal stem cells attenuate radicular pain by inhibiting microglial activation in a rat noncompressive disk herniation model.
Authors: Huang X, Wang W, Liu X, Xi Y, Yu J, Yang X, Ye X
Published: 2018 Oct - Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.
Authors: Serakinci N, Savtekin G
Published: 2017 - Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy.
Authors: Daly CD, Ghosh P, Zannettino ACW, Badal T, Shimmon R, Jenkin G, Oehme D, Jain K, Sher I, Vais A, Cohen C, Chandra RV, Goldschlager T
Published: 2018 Mar - Equiaxial Strain Modulates Adipose-derived Stem Cell Differentiation within 3D Biphasic Scaffolds towards Annulus Fibrosus.
Authors: Elsaadany M, Winters K, Adams S, Stasuk A, Ayan H, Yildirim-Ayan E
Published: 2017 Oct 9 - Immunomodulation of mesenchymal stem cells in discogenic pain.
Authors: Miguélez-Rivera L, Pérez-Castrillo S, González-Fernández ML, Prieto-Fernández JG, López-González ME, García-Cosamalón J, Villar-Suárez V
Published: 2018 Feb - Age-Correlated Phenotypic Alterations in Cells Isolated From Human Degenerated Intervertebral Discs With Contained Hernias.
Authors: Molinos M, Cunha C, Almeida CR, Gonçalves RM, Pereira P, Silva PS, Vaz R, Barbosa MA
Published: 2018 Mar 1 - Treatment of chronic low back pain - new approaches on the horizon.
Authors: Knezevic NN, Mandalia S, Raasch J, Knezevic I, Candido KD
Published: 2017 - Bone Marrow-Derived Mesenchymal Stem Cells as Autologous Therapy in Dogs with Naturally Occurring Intervertebral Disc Disease: Feasibility, Safety, and Preliminary Results.
Authors: Steffen F, Smolders LA, Roentgen AM, Bertolo A, Stoyanov J
Published: 2017 Nov - Biological Behavior of Human Nucleus Pulposus Mesenchymal Stem Cells in Response to Changes in the Acidic Environment During Intervertebral Disc Degeneration.
Authors: Liu J, Tao H, Wang H, Dong F, Zhang R, Li J, Ge P, Song P, Zhang H, Xu P, Liu X, Shen C
Published: 2017 Jun 15 - Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration.
Authors: Cunha C, Almeida CR, Almeida MI, Silva AM, Molinos M, Lamas S, Pereira CL, Teixeira GQ, Monteiro AT, Santos SG, Gonçalves RM, Barbosa MA
Published: 2017 Mar - Myofibroblast in the ligamentum flavum hypertrophic activity.
Authors: Hur JW, Bae T, Ye S, Kim JH, Lee S, Kim K, Lee SH, Kim JS, Lee JB, Cho TH, Park JY, Hur JK
Published: 2017 Aug - Biomimetic nucleus pulposus scaffold created from bovine caudal intervertebral disc tissue utilizing an optimal decellularization procedure.
Authors: Fernandez C, Marionneaux A, Gill S, Mercuri J
Published: 2016 Dec - Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study.
Authors: Elabd C, Centeno CJ, Schultz JR, Lutz G, Ichim T, Silva FJ
Published: 2016 Sep 1 - Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.
Authors: Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H
Published: 2016 Aug 16 - Concise Review: Stem Cell Trials Using Companion Animal Disease Models.
Authors: Hoffman AM, Dow SW
Published: 2016 Jul - Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs.
Authors: Kim Y, Lee SH, Kim WH, Kweon OK
Published: 2016 Mar - Cell-Based Therapies for Lumbar Discogenic Low Back Pain: Systematic Review and Single-Arm Meta-analysis.
Authors: Wu T, Song HX, Dong Y, Li JH
Published: 2018 Jan 1 - Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration.
Authors: Lin X, Fang X, Wang Q, Hu Z, Chen K, Shan Z, Chen S, Wang J, Mo J, Ma J, Xu W, Qin A, Fan S
Published: 2016 Mar 15 - Global Gene Expression Profiling and Alternative Splicing Events during the Chondrogenic Differentiation of Human Cartilage Endplate-Derived Stem Cells.
Authors: Shang J, Fan X, Shangguan L, Liu H, Zhou Y
Published: 2015 - Determination of the potential of induced pluripotent stem cells to differentiate into mouse nucleus pulposus cells in vitro.
Authors: Liu K, Chen Z, Luo XW, Song GQ, Wang P, Li XD, Zhao M, Han XW, Bai YG, Yang ZL, Feng G
Published: 2015 Oct 16 - Intraspinal Transplantation of Autologous Neurogenically-Induced Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Paraplegic Dogs without Deep Pain Perception Secondary to Intervertebral Disk Disease.
Authors: Besalti O, Can P, Akpinar E, Aktas Z, Elcin AE, Elcin YM
Published: 2015 - Potential and limitations of intervertebral disc endogenous repair.
Authors: Li Z, Peroglio M, Alini M, Grad S
Published: 2015 - Adverse effects of stromal vascular fraction during regenerative treatment of the intervertebral disc: observations in a goat model.
Authors: Detiger SE, Helder MN, Smit TH, Hoogendoorn RJ
Published: 2015 Sep - A combined biomaterial and cellular approach for annulus fibrosus rupture repair.
Authors: Pirvu T, Blanquer SB, Benneker LM, Grijpma DW, Richards RG, Alini M, Eglin D, Grad S, Li Z
Published: 2015 Feb - Intervertebral Disc Engineering through Exploiting Mesenchymal Stem Cells: Progress and Perspective.
Authors: Tam WK, Cheung KM, Leung VY
Published: 2016 - Duration of TGF-β3 Exposure Impacts the Chondrogenic Maturation of Human MSCs in Photocrosslinked Carboxymethylcellulose Hydrogels.
Authors: Gupta MS, Nicoll SB
Published: 2015 May - Enhancing cell migration in shape-memory alginate-collagen composite scaffolds: In vitro and ex vivo assessment for intervertebral disc repair.
Authors: Guillaume O, Naqvi SM, Lennon K, Buckley CT
Published: 2015 Apr - Gene expression profile analysis of human mesenchymal stem cells from herniated and degenerated intervertebral discs reveals different expression of osteopontin.
Authors: Marfia G, Navone SE, Di Vito C, Tabano S, Giammattei L, Di Cristofori A, Gualtierotti R, Tremolada C, Zavanone M, Caroli M, Torchia F, Miozzo M, Rampini P, Riboni L, Campanella R
Published: 2015 Feb 1 - Molecular basis of intervertebral disc degeneration and herniations: what are the important translational questions?
Authors: Kadow T, Sowa G, Vo N, Kang JD
Published: 2015 Jun - Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system.
Authors: Chon BH, Lee EJ, Jing L, Setton LA, Chen J
Published: 2013 Oct 2 - Stem cell regeneration of degenerated intervertebral discs: current status (update).
Authors: Gilbert HT, Hoyland JA, Richardson SM
Published: 2013 Dec - Stemming the Degeneration: IVD Stem Cells and Stem Cell Regenerative Therapy for Degenerative Disc Disease.
Authors: Sivakamasundari V, Lufkin T
Published: 2013 - Familial occurrence of pulmonary embolism after intravenous, adipose tissue-derived stem cell therapy.
Authors: Jung JW, Kwon M, Choi JC, Shin JW, Park IW, Choi BW, Kim JY
Published: 2013 Sep - Neuroprotective effects of mesenchymal stem cells on spinal motoneurons following ventral root axotomy: synapse stability and axonal regeneration.
Authors: Spejo AB, Carvalho JL, Goes AM, Oliveira AL
Published: 2013 Oct 10 - Construction of a tissue-engineered annulus fibrosus.
Authors: Cho H, Park SH, Park K, Shim JW, Huang J, Smith R, Elder S, Min BH, Hasty KA
Published: 2013 Jul